Zhiyu Dai, PhD

Zhiyu Dai, PhD portrait
    • Primary Address
    • Office
    • University of Arizona College of Medicine - Phoenix
    • 475 North 5th Street
    • Phoenix, AZ, United States 85004

Research

Research Statement

The research interest in the laboratory is studying the cellular mechanisms for severe pulmonary vascular remodeling in pulmonary hypertension and the identification of novel targets for pulmonary hypertension. The lab employs state-of-the-art technologies including genetic lineage tracing, genetic depletion, genetic reporter, and CRISPR-mediated genomic editing, AAV, single-cell RNA-sequencing as well as patient samples to study the molecular mechanisms of pulmonary vascular remodeling and identify novel therapeutics for this devastating disease. The lab is funded by NHLBI Pathway to Independence Award (Parent K99/R00), AHA Career Development Award and ATS Foundation Research Program.

Area of Expertise

  • Pulmonary Hypertension (Research)
  • Lung Vascular Biology (Research)
  • Cardiopulmonary Disease (Research)