Inna P. Gladysheva, PhD

Inna P Gladysheva, Ph.D., is a Professor of Medicine and Clinical Translational Science at the University of Arizona, College of Medicine-Phoenix (UA-COM-P) and a member of the Translational Cardiovascular Research Center. Dr. Gladysheva earned a master's degree in chemistry and Ph.D. in enzyme kinetics and biochemistry from Lomonosov Moscow State University, Russia, and completed a research fellowship in targeted drug delivery at Lomonosov Moscow State University and in cardiovascular biology and diseases at Harvard University's School of Public Health, Boston, MA. Prior to joining the UA COM-P, she was an Associate Professor of Medicine at the Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, and an Assistant Professor of Medicine at the Medical College of Georgia, Augusta, GA. Dr. Gladysheva translational research, which AHA and NIH funded, focuses on the molecular and pathophysiologic mechanisms of cardiomyopathy, heart failure, and concurrent complications to delay or prevent the transition from cardiac dysfunction (cardiomyopathies) to symptomatic HFrEF. Specifically, she is interested in proteases and hormones as potential diagnostic and therapeutic targets, and not pharmacological approaches (lifestyle choices) to modulate the progression of cardiomyopathy and the development of edema/congestion that signifies heart failure. Dr. Gladyshev has successfully contributed to multiple research projects on regulating uncontrolled proteolysis in cardiovascular disorders associated with thrombosis, cardiomyopathies, and HFrEF.